The error message “Cannot start Microsoft Outlook” can be caused by various reasons, such as a corrupted Outlook profile, incompatible add-ins, damaged Outlook data files, or issues with the Outlook program itself.
This solution is a quick way to determine if any add-ins are causing the issue. Safe Mode starts Outlook without loading any add-ins and checks for issues with the Outlook data files.
Outlook permits customers to personalize the navigation pane. Sometimes, customizations can prevent Microsoft Outlook from starting. Resetting the navigation pane may resolve this issue.
If your Outlook data files are corrupted, you can use the built-in Inbox Repair Tool (SCANPST.EXE) to fix them.
If the issue persists, repairing the Office application may help.
If repairing does not resolve the issue, you may need to uninstall and reinstall Microsoft Office.
If the issue persists, it may be due to a corrupted Outlook profile. Create a new profile to resolve this.
If a third-party add-in is causing the issue, disable it to resolve the problem.
If none of the above solutions work, reinstalling Microsoft Outlook may fix the issue.
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